Description

About The Book

Nutrigenomics explores how diet interacts with genes to influence health and disease. It combines nutrition, genomics, and molecular biology to understand how nutrients affect gene expression, metabolism, and disease risk. Unlike traditional nutrition, which offers generalized dietary guidelines, nutrigenomics tailors recommendations based on genetic variations, enabling personalized nutrition strategies.

Key themes include:
1. Gene-Diet Interactions: Genetic polymorphisms (e.g., lactase persistence or APOA2 variants) determine how individuals metabolize nutrients, influencing responses to fats, carbohydrates, and micronutrients.
2. Epigenetics: Nutrients can modify gene expression through DNA methylation or histone changes, as seen in studies linking fetal malnutrition (e.g., the Dutch Hunger Winter) to adult metabolic diseases.
3. Chronic Disease Prevention: Nutrigenomics addresses conditions like obesity, diabetes, and cardiovascular diseases by identifying genetic risks (e.g., MTHFR mutations requiring folate adjustments) and dietary interventions.
4. Microbiome Integration: Gut microbiota interact with dietary components (e.g., probiotics or fiber) to modulate inflammation, immunity, and nutrient absorption, impacting conditions from IBS to cancer.
5. Technological Advances: Omics tools (metabolomics, proteomics) and AI help decode individual nutrient needs, though challenges remain in translating research into practical dietary advice.

About The Author

The author is Periodontist and Craniofacial surgeon who is having 16 years experience in applied immunology and genetics. He practices in Bangalore and currently he is a CEO and founder of two companies related to healthcare immunology and applied genomics.